
P&O Mediterranean Cruises
It is one of the world’s most popular holiday destinations, and when guests sail there with P&O Cruises, they will understand what makes the Mediterranean such an incredible cruising experience. From world-renowned cuisines to beaches that have to be seen to be believed, this destination has no shortage of ways to impress cruisers.

Why Sail with P&O Cruises to the Mediterranean?
For 180 years, P&O Cruises has promised adventure and fun and delivered on that promise time and time again. Across its exceptional fleet, the cruise line offers everything guests could need to enjoy every moment of their Mediterranean cruise, from international dining venues to kids’ clubs and fitness facilities.
As they explore the Mediterranean, P&O Cruises ensures that families and couples can make the most of every moment. Its variety of cabins and staterooms means every party can feel right at home, no matter where they are in the region, and P&O’s team of exceptional chefs can echo in-port experiences with dishes that explore the Mediterranean’s wealth of culinary flair.
What Are the Best P&O Mediterranean Cruise Destinations?
The Mediterranean is such a rich and diverse region, home to so many historic nations and culinary favourites. With a P&O itinerary, guests can experience it all, enjoying exceptional British service along the way. Here are some of the top ports that guests can discover with P&O Mediterranean cruises:

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Frequently Asked Questions
Guests can choose the length of the P&O Mediterranean cruise that suits them. The shortest voyages range from 6 to 9 nights, primarily sailing from Malta. For longer voyages, guests can sail around the Mediterranean for up to 24 nights (13 ports), sailing from Southampton.
The shoulder seasons of September to November and March to May offer the best deals for sailing around the Mediterranean. These periods combine slightly cooler weather with fewer crowds.

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Enjoy Last-Minute Voyages from P&O Cruises
With 180 years of experience delivering exceptional holidays, P&O Cruises has all the facilities and expertise guests need to make their last-minute travel dreams a reality! If the urge to sail strikes, choose from a wide range of destinations and itineraries and get set for an escape that feels even better without the wait.
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We found
241 cruises


- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain


- Departure - Southampton, Great Britain
- 8 stops
- Arrival - Southampton, Great Britain


- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain


- Departure - Santa Cruz, Tenerife
- 13 stops
- Arrival - Malaga, Spain


- Departure - Santa Cruz, Tenerife
- 13 stops
- Arrival - Malaga, Spain


- Departure - Santa Cruz, Tenerife
- 8 stops
- Arrival - Malaga, Spain


- Departure - Santa Cruz, Tenerife
- 8 stops
- Arrival - Malaga, Spain


- Departure - Santa Cruz, Tenerife
- 16 stops
- Arrival - Santa Cruz, Tenerife


- Departure - Santa Cruz, Tenerife
- 16 stops
- Arrival - Santa Cruz, Tenerife


- Departure - Santa Cruz, Tenerife
- 8 stops
- Arrival - Malaga, Spain









