P&O Cruises from Southampton
All 7 of the P&O Cruises fleet sail out of Southampton - Arcadia, Aurora, Azura, Britannia, Ventura and their newest ships Arvia and Iona so you will be spoiled for choice.
Our most popular P&O Cruises sailing from Southampton are: 2 weeks Mediterranean, 2 weeks Canary Islands, 1 or 2 week Northern Europe/Fjords & 2 weeks in the Caribbean. In addition we have a wide selection of other P&O cruises from Southampton ranging from South America, Eastern USA and Canada as well as the ever popular World Cruises for those looking for an adventure.
In the search results below we show the next available P&O cruises sailing from Southampton. You can filter these results by price to show the cheapest cruises at the top. Or your favourite destination, ship or holiday duration on the left. Or search the results for the date you would like to take you P&O cruise holiday from Southampton.
All of our P&O Cruises Southampton sailings have all inclusive full board dining and include all gratuities. If you would like to cover your bar tab before you embark at Southampton then you may like to consider adding on a drink package to your booking.
To find out more about which fare is best for you - Select Fare, Early Saver or Saver fares, see our guide to P&O fares.
If you need some more advice our friendly Cruise Agents are looking forward to speaking to you on 01246 819 819 or you can book your cruise online today.
Southampton
P&O Cruises
We found
251 cruises
1 / 25
Discount
Duration
12 nights
Date
17 Nov 2026
Ship
Ventura
- Departure - Southampton, Great Britain
- 7 stops
- Arrival - Southampton, Great Britain
Show all departures (2)
1 / 36
Discount
Duration
14 nights
Date
21 Nov 2026
Ship
Iona
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
1 / 27
Discount
Duration
14 nights
Date
27 Nov 2026
Ship
Aurora
- Departure - Southampton, Great Britain
- 8 stops
- Arrival - Southampton, Great Britain
1 / 25
Discount
Duration
4 nights
Date
29 Nov 2026
Ship
Ventura
- Departure - Southampton, Great Britain
- 4 stops
- Arrival - Southampton, Great Britain
Show all departures (2)
1 / 27
Discount
Duration
3 nights
Date
30 Nov 2026
Ship
Arcadia
- Departure - Southampton, Great Britain
- 3 stops
- Arrival - Southampton, Great Britain
1 / 25
Discount
Duration
18 nights
Date
3 Dec 2026
Ship
Ventura
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
1 / 27
Discount
Duration
18 nights
Date
3 Dec 2026
Ship
Arcadia
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
1 / 36
Discount
Duration
14 nights
Date
5 Dec 2026
Ship
Iona
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
1 / 27
Discount
Duration
4 nights
Date
11 Dec 2026
Ship
Aurora
- Departure - Southampton, Great Britain
- 4 stops
- Arrival - Southampton, Great Britain
Show all departures (4)
1 / 27
Discount
Duration
14 nights
Date
15 Dec 2026
Ship
Aurora
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
Show all departures (3)
1 / 36
Discount
Duration
16 nights
Date
19 Dec 2026
Ship
Iona
- Departure - Southampton, Great Britain
- 10 stops
- Arrival - Southampton, Great Britain
1 / 25
Discount
Duration
14 nights
Date
21 Dec 2026
Ship
Ventura
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
1 / 27
Discount
Duration
16 nights
Date
21 Dec 2026
Ship
Arcadia
- Departure - Southampton, Great Britain
- 10 stops
- Arrival - Southampton, Great Britain
1 / 27
Discount
Duration
5 nights
Date
29 Dec 2026
Ship
Aurora
- Departure - Southampton, Great Britain
- 5 stops
- Arrival - Southampton, Great Britain
Show all departures (2)
1 / 27
Discount
Duration
75 nights
Date
3 Jan 2027
Ship
Aurora
- Departure - Southampton, Great Britain
- 39 stops
- Arrival - Southampton, Great Britain
1 / 25
Discount
Duration
14 nights
Date
4 Jan 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
1 / 36
Discount
Duration
35 nights
Date
4 Jan 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 13 stops
- Arrival - Southampton, Great Britain
1 / 27
Discount
Duration
106 nights
Date
6 Jan 2027
Ship
Arcadia
- Departure - Southampton, Great Britain
- 38 stops
- Arrival - Southampton, Great Britain
1 / 25
Discount
Duration
7 nights
Date
18 Jan 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
1 / 25
Discount
Duration
14 nights
Date
25 Jan 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
1 / 25
Discount
Duration
4 nights
Date
8 Feb 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 4 stops
- Arrival - Southampton, Great Britain
Show all departures (5)
1 / 36
Discount
Duration
5 nights
Date
8 Feb 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 5 stops
- Arrival - Southampton, Great Britain
1 / 25
Discount
Duration
14 nights
Date
12 Feb 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
1 / 36
Discount
Duration
7 nights
Date
13 Feb 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (2)
1 / 25
Discount
Duration
21 nights
Date
26 Feb 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 12 stops
- Arrival - Southampton, Great Britain
Show all departures (2)
1 / 36
Discount
Duration
14 nights
Date
27 Feb 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 8 stops
- Arrival - Southampton, Great Britain
1 / 36
Discount
Duration
14 nights
Date
13 Mar 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
2 Available promotions:
PRICE DROP GUARANTEE, UP TO £500 SAVINGS
1 / 27
Discount
Duration
14 nights
Date
19 Mar 2027
Ship
Aurora
- Departure - Southampton, Great Britain
- 8 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 36
Discount
Duration
7 nights
Date
27 Mar 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 24
Discount
Duration
7 nights
Date
28 Mar 2027
Ship
Arvia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (4)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 25
Discount
Duration
3 nights
Date
31 Mar 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 3 stops
- Arrival - Southampton, Great Britain
Show all departures (3)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
7 nights
Date
2 Apr 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (9)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
14 nights
Date
2 Apr 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 11 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 27
Discount
Duration
19 nights
Date
2 Apr 2027
Ship
Aurora
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 36
Discount
Duration
7 nights
Date
3 Apr 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (12)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 25
Discount
Duration
14 nights
Date
3 Apr 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
Show all departures (17)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
7 nights
Date
9 Apr 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 24
Discount
Duration
14 nights
Date
11 Apr 2027
Ship
Arvia
- Departure - Southampton, Great Britain
- 11 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
3 nights
Date
16 Apr 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 3 stops
- Arrival - Southampton, Great Britain
Show all departures (2)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 25
Discount
Duration
14 nights
Date
17 Apr 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 24
Discount
Duration
7 nights
Date
18 Apr 2027
Ship
Arvia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (16)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
4 nights
Date
19 Apr 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 4 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
7 nights
Date
23 Apr 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 36
Discount
Duration
7 nights
Date
24 Apr 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (7)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 24
Discount
Duration
7 nights
Date
25 Apr 2027
Ship
Arvia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (3)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 27
Discount
Duration
19 nights
Date
25 Apr 2027
Ship
Aurora
- Departure - Southampton, Great Britain
- 9 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
7 nights
Date
30 Apr 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (3)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 25
Discount
Duration
7 nights
Date
1 May 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (2)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 24
Discount
Duration
7 nights
Date
2 May 2027
Ship
Arvia
- Departure - Southampton, Great Britain
- 5 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 24
Discount
Duration
14 nights
Date
9 May 2027
Ship
Arvia
- Departure - Southampton, Great Britain
- 8 stops
- Arrival - Southampton, Great Britain
Show all departures (3)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 27
Discount
Duration
14 nights
Date
13 May 2027
Ship
Arcadia
- Departure - Southampton, Great Britain
- 10 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
7 nights
Date
14 May 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 27
Discount
Duration
12 nights
Date
14 May 2027
Ship
Aurora
- Departure - Southampton, Great Britain
- 8 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
7 nights
Date
21 May 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (5)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 25
Discount
Duration
7 nights
Date
22 May 2027
Ship
Ventura
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (3)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 36
Discount
Duration
7 nights
Date
22 May 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (16)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 27
Discount
Duration
7 nights
Date
26 May 2027
Ship
Aurora
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 27
Discount
Duration
7 nights
Date
27 May 2027
Ship
Arcadia
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (2)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 28
Discount
Duration
7 nights
Date
28 May 2027
Ship
Britannia
- Departure - Southampton, Great Britain
- 5 stops
- Arrival - Southampton, Great Britain
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
1 / 36
Discount
Duration
7 nights
Date
29 May 2027
Ship
Iona
- Departure - Southampton, Great Britain
- 6 stops
- Arrival - Southampton, Great Britain
Show all departures (14)
4 Available promotions:
PRICE DROP GUARANTEE, SAVE35 – £35 off when you spend £1,800, SAVE70 – £70 off when you spend £3,600, UP TO £500 SAVINGS
60 of 251 pcs